Major histocompatibility complex regulation of the immune response.
نویسندگان
چکیده
The ability of an organism to distinguish self from nonself is determined by a cluster of genes located in the major histocompatibility complex. Recent advances in molecular genetics and cellular immunology have begun to elucidate the mechanisms responsible for immune response regulation. In this review article, the genetic organization of the murine and human major histocompatibility complexes and the manner by which their gene products modulate immune responsiveness are discussed.
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عنوان ژورنال:
- The Journal of surgical research
دوره 39 2 شماره
صفحات -
تاریخ انتشار 1985